QuantiGene 2.0 Assay
QuantiGene 2.0 Assay - Complete Bibliography (Updated 05-05-2014) PDF
QuantiGene 2.0 Assay - Bibliography 2011-2014 (Updated 05-05-2014) PDF
Berhanu T. K., et al. Increased AMP-activated protein kinase in skeletal muscles of Murphy Roth Large mice and its potential role in altered metabolism. Physiological Reports 2(3) (2014).
Bowling A. J., Pence H. E. and Church J. B. Application of a Novel and Automated Branched DNA in Situ Hybridization Method for the Rapid and Sensitive Localization of mRNA Molecules in Plant Tissues. Applications in Plant Sciences 2(4):1400011 (2014).
Dong Y., et al. Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo. Adv Healthc Mater (2014).
Dubelman S., et al. Environmental Fate of Double-Stranded RNA in Agricultural Soils. PLoS ONE 9(3):e93155 (2014).
Rice E. A., et al. Expression of a Truncated ATHB17 Protein in Maize Increases Ear Weight at Silking. PLoS ONE 9(4):e94238 (2014).
Sandoz K. M., et al. Developmental transitions of Coxiella burnetii grown in axenic media. J Microbiol Methods 96:104-10 (2014).
Sinnamon J. R. and Czaplinski K. RNA detection in situ with FISH-STICs. RNA 20(2):260-6 (2014).
Takeuchi K., et al. EGF-Like-Domain-7 Is Required for VEGF-Induced Akt/ERK Activation and Vascular Tube Formation in an Ex Vivo Angiogenesis Assay. PLoS ONE 9(3):e91849 (2014).
Voss C., et al. A novel, non-radioactive eukaryotic in vitro transcription assay for sensitive quantification of RNA polymerase II activity. BCM Mol Biol 15(1):7 (2014).
Xue L., et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells J Allergy Clin Immunol (2014).
Zhang Y., et al. Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice. Toxicol Appl Pharmacol (2014).
Boess F., et al. Effect of GLP-1R agonists taspoglutide and liraglutide on primary thyroid C-cells. J Mol Endocrinol (2013).
Bonnet M. E., et al. Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition. J Control Release (2013).
Chapuis J., et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry (2013).
Chen K., et al. Value of circulating cell-free DNA in diagnosis of hepatocelluar carcinoma. World J Gastroenterol 19(20):3143-9 (2013).
Cheng Z., et al. A novel, sensitive assay for high-throughput molecular detection of plasmodia for active screening of malaria for elimination. J Clin Microbiol 51(1):125-30 (2013).
Crevecoeur J., et al. Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis. Neuropathol Appl Neurobiol (2013).
Erba H. P., et al. Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML). Invest New Drugs (2013).
Esposito G., et al. Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-alpha activation. Gut (2013).
Hazalin N. A., et al. Apoptosis induced by desmethyl-lasiodiplodin is associated with upregulation of apoptotic genes and downregulation of monocyte chemotactic protein-3. Anti-Cancer Drugs (2013).
Kedinger V., et al. Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases. BMC Cancer 13(338 (2013).
Kovacs T., Kelemen O. and Keri S. Decreased fragile X mental retardation protein (FMRP) is associated with lower IQ and earlier illness onset in patients with schizophrenia. Psychiatry Res (2013).
Liu H., et al. Association study of TOLL and CARD with leprosy susceptibility in Chinese population. Hum Mol Genet (2013).
Lutter E. I., et al. Chlamydia trachomatis Inclusion Membrane Protein CT228 Recruits Elements of the Myosin Phosphatase Pathway to Regulate Release Mechanisms. Cell Rep (2013).
Maier M. A., et al. Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics. Mol Ther (2013).
Mazzuferi M., et al. Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy. Ann Neurol (2013).
Mercken E. M., et al. Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile. Aging Cell (2013).
Miura D., Iwatani T. and Kawabata H. Mechanisms of primary AI resistance in ER-positive HER2-negative breast cancer. 2013 ASCO Annual Mtg Proc (Post-Meeting Edition) 31(15, May 20 Sup):E11519 (2013).
Mukund S., et al. Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. J Biol Chem 288(50):36168-78 (2013).
Ooi Y. S., et al. Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry. PLoS Pathog 9(12):e1003835 (2013).
Patel P. R., et al. Genomic Signature Predicts Resistance To Busulfan In AML Cell Lines. Blood 122(21):3850 (2013).
Piccinni M. P., et al. Potential pathogenetic role of Th17, Th0, and Th2 cells in erosive and reticular oral lichen planus. Oral Dis (2013)
Plovanich M., et al. MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. PLoS ONE 8(2):e55785 (2013).
Sahay G., et al. Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nat Biotechnol (2013).
Storey K. B. and Wu C. W. Stress response and adaptation: A new molecular toolkit for the 21st century. Comp Biochem Physiol A Mol Integr Physiol (2013).
Trabzuni D., et al. Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus. PLoS ONE 8(8):e70724 (2013).
Zhang M., et al. Alteration of circulating mitochondrial DNA concentration after irradiation. Adv Exp Med Biol 765(371-7 (2013).
Zurek O. W., et al. The Role of Innate Immunity in Promoting SaeR/S-Mediated Virulence in Staphylococcus aureus. J Innate Immun (2013).
Burgess A., et al. Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression. J Control Release (2012).
Cheng X. & Klasseen C. D. Hormonal and chemical regulation of paraoxonases in mice. J Pharmacol Exp Ther 342(3):688-95 (2012).
Cheng Z., et al. Towards Active Screening of Malaria for Elimination: A Novel, Sensitive Assay for High Throughput Molecular Detection of Plasmodia. J Clin Microbiol (2012).
Conforto T. L., et al. Impact of CUX2 on the Female Mouse Liver Transcriptome: Activation of Female-biased Genes and Repression of Male-biased Genes. Mol Cell Biol (2012).
Cui J. Y., et al. Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice. Am J Physiol Gastrointest Liver Physiol (2012).
Desai A., et al. META060 attenuates TNF-alpha-activated inflammation, endothelial-monocyte interactions, and matrix metalloproteinase-9 expression, and inhibits NF-kappaB and AP-1 in THP-1 monocytes. Athersclerosis 223(1):130-6 (2012).
Dunmore R., et al. An assessment of epithelial and mesenchymal phenotypes in experimental and clinical pulmonary fibrosis. ISRN Pulmonology Volume 2012 (2012).
Foster D. J., et al. Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo. Rna 18(3):557-68 (2012).
Hummon A. B., et al. Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Molecular Cancer 11(1) (2012).
Jiao X., et al. Discovery and optimization of a series of liver X receptor antagonists. Bioorg Med Chem Lett 22(18):5966-70 (2012).
Kim H. R., et al. Fibroblast Growth Factor Receptor 1 Gene Amplification Is Associated With Poor Survival and Cigarette Smoking Dosage in Patients With Resected Squamous Cell Lung Cancer. J Clin Oncol (2012).
Koth C. M., et al. Molecular basis for negative regulation of the glucagon receptor. Proc Natl Acad Sci USA 109(36):14393-8 (2012).
Li X., et al. [Angiotensin (1-7) inhibits angiotensin II-stimulated expression of connective tissue growth factor mRNA in hepatic stellate cells.] Zhonghua Gan Zang Bing Za Zhi 20(6):458-62 (2012).
Linton K., et al. Microarray gene expression analysis of fixed archival tissue permits molecular classification and identification of potential therapeutic targets in diffuse large B-cell lymphoma. J Mol Diagn 14(3):223-32 (2012).
Meng X. L., et al. Low expression of stathmin in tumor predicts high response to neoadjuvant chemotherapy with docetaxel-containing regimens in locally advanced breast cancer. Genet Test Mol Biomarkers (2012).
Metzgera D. C., et al. Normalizing for biology: Accounting for technical and biological variation in levels of reference gene and insulin-like growth factor 1 (igf1) transcripts in fish livers. Comp Biochem and Physiol (2012).
Mounier A., et al. Genetic complexity in the BIN1 locus. Journal of the Alzheimers Association 8(1, Supp.):P663-4 (2012).
Muller P., Pugazhendhi D., Ziedler M. P. Modulation of human JAK-STAT pathway signaling by functionally conserved regulators. JAK-STAT 1(1):1-11 (2012).
Patani R., et al. Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis. J Neurochem 122(4):738-51 (2012).
Pettersen J. C., et al. The PPAR-alpha agonists fenofibrate and CP-778875 cause increased beta-oxidation, leading to oxidative injury in skeletal and cardiac muscle in the rat. Toxicol Pathol (2012).
Phan J. H., Quo, C. F. & Want, M. D. Cardiovascular genomics: a biomarker identification pipeline. IEEE Trans Inf Technol Biomed 16(5):809-22 (2012).
Querbes W., et al. Treatment of erythropoietin deficiency in mice with systemically administered siRNA. Blood 120(9):1916-22 (2012).
Ruangsiriluk W., et al. Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression. J Lipid Res (2012).
Sarveswaran J., et al. Cytokine gene expression profiling identifies distinct patterns in severe sepsis. Nucleic Acid Ther 22(5):344-59 (2012).
Schneider B., et al. Targeted siRNA delivery and mRNA knockdown mediated by bispecific digoxigenin-binding antibodies. Mole Ther Nucleic Acids 1(9):e46 (2012).
Schwartz J. R., et al. A facile, branched DNA assay to quantitatively measure glucocorticoid receptor auto-regulation in T-cell acute lymphoblastic leukemia. Chin J Cancer> 31(8):381-91 (2012).
Sciabola S., et al. Improved nucleic acid descriptors for siRNA efficacy prediction. Nucleic Acids Res (2012).
Shahnazari M., et al. Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice. Bone 50(3):628-37 (2012).
Siah A., Johnson G., Berthe F. C. Single Plex Branched DNA as an Alternative Assay to Quantify P53-Like mRNA Levels in Softshell Clam Mya arenaria Hemocytes. Journal of Shellfish Research 31(3):691-96 (2012).
Stanton R., et al. Chemical modification study of antisense gapmers. Nucleic Acid Ther 22(5):344-59 (2012).
Tanguy M., et al. Functional and molecular responses in Mytilus edulis hemocytes exposed to bacteria, Vibrio splendidus. Dev Comp Immunol (2012).
Trabzuni D., et al. MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies. Hum Mol Genet 21(18):4094-103 (2012).
Wen X., et al. Regulation of hepatic phase-II metabolism in pregnant mice. J Pharmacol Exp Ther (2012).
Zhang L., et al. Radiation-induced elevation of plasma DNA in mice is associated with genomic background. Adv Exp Med Biol 737:147-53 (2012).
Zhang Y., et al. Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile Acid metabolism in mice. PLoS ONE 7(3):e34522 (2012).
Zhang Y., et al. Transcription factor-mediated regulation of carboxylesterase enzymes in livers of mice. Drug Metab Dispos (2012).
Babij C., et al. STK33 kinase activity is nonessential in KRAS-dependent cancer cells. Cancer Res (2011).
Baughman J. M., et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature (2011).
Beare P. A., et al. Dot/Icm Type IVB secretion system requirements for Coxiella burnetii growth in human macrophages. MBio 2(4) (2011).
Bergemann T. L., Wilson J. Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics. BMC Bioinformatics 12(1):228 (2011).
Brown M. L., et al. Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit. Bioorg Med Chem Lett 21(18):5206-9 (2011).
Cao G., et al. Evacetrapib is a novel, potent and selective inhibitor of cholesteryl ester transfer protein that elevates high-density lipoprotein cholesterol without inducing aldosterone or increasing blood pressure. Journal of Lipid Research (2011).
Cao Y. C., et al. Quantum dots high fluorescent signal amplification immunoassay using branched DNA and peptide nucleic acid conjugated antibody. Analyst (2011).
Chae B. J., et al. Measurement of ER and PR status in breast cancer using the QuantiGene2.0 assay. Pathology 43(3):248-53 (2011).
Crombez L., et al. A non-covalent peptide-based strategy for ex vivo and in vivo oligonucleotide delivery. Methods Mol Biol 764:59-73 (2011).
Hinfray N. et al. Characterization of testicular expression of P450 17alpha-hydroxylase, 17,20-lyase in zebrafish and its perturbation by the pharmaceutical fungicide clotrimazole. Gen Comp Endocrinol (2011).
Kadota K., et al. Evaluating methods for ranking differentially expressed genes applied to MicroArray Quality Control data. BMC Bioinformatics 12(1):227 (2011).
Lapierre J., et al. Potent and systematic RNAi mediated silencing with single oligonucleotide compounds. Rna 17(6):1032-7 (2011).
Li M., et al. Mutant hypoxia inducible factor-1alpha improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle. Microvasc Res 81(1):26-33 (2011).
Liao L. H., et al. Single-nucleotide polymorphisms and haplotype of CYP2E1 gene associated with systemic lupus erythematosus in Chinese population. Arthritis Res Ther 13(1):R11 (2011).
Lu B., et al. The role of the transcription factor SIM2 in prostate cancer. PLoS ONE 6(12):e28837 (2011).
Lu H., et al. Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis. Toxicol Appl Pharmacol (2011).
Martin S. E., et al. RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors. Curr Cancer Drug Targets (2011).
Mital J., et al. A role for the Src-family kinase Fyn in sphingolipid acquisition by chlamydiae. Infect Immun (2011).
Murray L. A., et al. TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. Int J Biochem Cell Biol 43(1):154-62 (2011).
Polach K. J., et al. Delivery of siRNA to the Mouse Lung via a Functionalized Lipopolyamine. Mol Ther (2011).
Selvaduray K. R., et al. Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cells. Genes Nutr (2011).
Torres J. Z., et al. The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Cell 147(6):1309-23 (2011).
Trabzuni D., et al. Quality control parameters on a large dataset of regionally-dissected human control brains for whole genome expression studies. J Neurochem (2011).
Voth D. E., et al. The Coxiella burnetii cryptic plasmid is enriched in genes encoding type IV secretion system substrates. J Bacteriol 193(7):1493-503 (2011).
Zheng W., Chung L. M., Zhao H. Bias detection and correction in RNA-Sequencing data. BMC Bioinformatics 12(1):290 (2011).
Abbott C., et al. Mouse monoclonal antibodies against human c-Mpl and characterization for flow cytometry applications. Hybridoma (Larchmt) 29(2):103-13 (2010).
Addepalli H., et al. Modulation of thermal stability can enhance the potency of siRNA. Nucleic Acids Res (2010).
Akashi M., et al. Noninvasive method for assessing the human circadian clock using hair follicle cells. Proc Natl Acad Sci USA 107(35):15643-8 (2010).
Aleksunes L. M., et al Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice. J Pharmacol Exp Ther 333(1):140-51 (2010).
Alnouti Y., et al. Mechanisms of gender-specific regulation of mouse sulfotransferases (Sults). Xenobiotica (2010).
Berahovich R. D., et al. CXCR7 protein is not expressed on human or mouse leukocytes. J Immunol (2010).
Chen Q., et al. Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery. J Control Release (2010).
Chen Z., et al. Validation of the biotic ligand model in metal mixtures: bioaccumulation of lead and copper. Environ Sci Technol 44(9):3580-6 (2010).
Cheneval D., et al. A review of methods to monitor the modulation of mRNA stability: a novel approach to drug discovery and therapeutic intervention. J Biomol Screen 15(6):609-22 (2010).
Cui J. Y., et al. Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver. Toxicol Sci (2010).
Cui J. Y., et al. ChIPing the cistrome of PXR in mouse liver. Nucleic Acids Res (2010).
Debruin C., et al. Most purported antibodies to the human granulocyte colony-stimulating factor receptor are not specific. Exp Hematol (2010).
Ehsani A., et al. Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV coreceptor CCR5. Mol Ther 18(4):796-802 (2010).
Erickson H. S., et al. High throughput screening of normal and neoplastic tissue samples. Comb Chem High Throughput Screen 13(3):253-67 (2010).
Furusato B., et al. ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification. Prostate Cancer Prostatic Dis 13(3):228-37 (2010).
Genter M. B., et al. Drug transporter expression and localization in rat nasal respiratory and olfactory mucosa and olfactory bulb. Drug Metab Dispos 38(10):1644-7 (2010).
Haobin W., et al. Detection and clinical significance of CEA,GCC and CD44v6 mRNA in peritoneal lavages of colorectal cancer patients:report of 60 cases. Acta Academiae Medicinae Militaris Tertiae 32(1):36-40 (2010).
Hardwick R. N., et al. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metab Dispos (2010).
Ibarra J. A., et al. Induction of Salmonella pathogenicity island 1 under different growth conditions can affect Salmonella-host cell interactions in vitro. Microbiology 156(Pt 4):1120-33 (2010).
Jeong I., et al. Role of ataxia telangiectasia mutated in insulin signalling of muscle-derived cell lines and mouse soleus. Acta Physiol (Oxf) 198(4):465-75 (2010).
Kaizerman J. A., et al. Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines. Bioorg Med Chem Lett 20(15):4607-10 (2010).
Lachaud A. A., et al. Werner's syndrome helicase participates in transcription of phenobarbital-inducible CYP2B genes in rat and mouse liver. Biochem Pharmacol 79(3):463-70 (2010).
Love K. T., et al. Lipid-like materials for low-dose, in vivo gene silencing. Proc Natl Acad Sci USA (2010).
Lucas B. S., et al. Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists. Bioorg Med Chem Lett 20(12):3618-22 (2010).
Monovich L., et al. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase. FEBS Lett 584(3):631-7 (2010).
Murray L. A., et al. Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages. PLoS One 5(3):e9683 (2010).
Musunuru K., et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466(7307):714-9 (2010).
Radaelli A., et al. Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits. J Transl Med 8:40 (2010).
Robertson B., et al. Specificity and functionality of microRNA inhibitors. Silence 1(1):10 (2010).
Salomon W., et al. Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC. Nucleic Acids Res (2010).
Sasu B. J., et al. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia. Blood 115(17):3616-24 (2010).
Semple S. C., et al. Rational design of cationic lipids for siRNA delivery. Nat Biotechnol (2010).
Srivastava S., et al. A two-parameter generalized Poisson model to improve the analysis of RNA-seq data. Nucleic Acids Res 38(17):e170 (2010).
Stevens A., et al. Epigenetic changes in the hypothalamic proopiomelanocortin and glucocorticoid receptor genes in the ovine fetus after periconceptional undernutrition. Endocrinology 151(8):3652-64 (2010).
Swift S., et al. Absence of functional EpoR expression in human tumor cell lines. Blood 115(21):4254-63 (2010).
Talbot D. C., et al. Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study. Clin Cancer Res 16(24):6150-8 (2010).
Wang L., et al. In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies. Drug Metab Dispos 38(3):448-58 (2010).
Yim H. W., et al. Branched- chain Assay for ER, PR, and HER2 RNA Levels is a Useful Adjunct in the Evaluation of ER, PR, and HER2 in Breast Cancer. J Breast Cancer 13(3):267-74 (2010).
Yue X., et al. Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini. Nat Chem Biol 6(8):621-9 (2010).
Zhang L., et al. A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma. Br J Radiol 83(992):694-701 (2010).
Zhang Y. K., et al. Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet. Toxicol Appl Pharmacol 245(3):326-34 (2010).
Zumbansen M., et al. First siRNA library screening in hard-to-transfect HUVEC cells. J RNAi Gene Silencing 6(1):354-60 (2010).